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Levitra 20mg

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Since most men do not need the largest 20 mg dose, it makes sense to have your doctor prescribe the 20 mg tablet and then to split it in half or in quarters as needed.

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LEVITRA - FAME (2)

Levitra 20mg film-coated tablets

Due to regulatory changes, the content of the following Patient Information Leaflet may vary from the one found in your medicine pack. Please compare the 'Leaflet prepared/revised date' towards the end of the leaflet to establish if there have been any changes.

If you have any doubts or queries about your medication, please contact your doctor or pharmacist.

This leaflet was last revised in 12/2015.

v023_0

Source: https://www.medicines.org.uk/emc/medicine/11753



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When to Take Levitra or Viagra

Dosage

The initial recommended dosage of Viagra for most patients is 50 mg about one hour before sexual activity. However, a person can take Viagra as little as 30 minutes or up to 4 hours before sexual activity. The initial 50 mg dose, taken no more than once daily, can be adjusted later depending on a person's responsiveness to the medication. Doses can be lowered to 25 mg or increased to as much as 100 mg daily.

Patients taking Levitra are usually started on a 10 mg dose, which they take no more than once daily, about one hour before sexual activity. It can take as little as 30 minutes for Levitra to work in some patients. Like with Viagra, Levitra dosages are adjusted depending on a person's reaction, with doctors generally decreasing doses to to 2.5 mg or increasing them to no more than 20 mg once a day.

Both medications require sexual stimulation for effectiveness. Although Viagra and Levitra can be taken with or without food, those taking the medications shouldavoid grapefruit and grapefruit juice, as both can diminish drug effectiveness. Similarly, greasy or fatty foods can delay absorption and effects.

How Levitra and Viagra Work

The following video features a physician explaining how PDE5 inhibitor drugs like Cialis, Viagra, and Levitra work and how they differ:

Efficacy

Vardenafil and sildenafil are effective in treating erectile dysfunction and pulmonary arterial hypertension. They are well-tolerated by patients, with few suffering from serious side effects. Additionally, Viagra (sildenafil) has recently been found to treat the symptoms of several other health conditions.

Levitra vs. Viagra Studies

  • Levitra very slightly outperformed Viagra in one study of men with erectile dysfunction and risk factors for cardiovascular disease, with more men preferring Levitra over Viagra (39% to 35%). Neither drug caused significant side effects.[1]
  • A 2011 comparison of studies of Cialis, Levitra, and Viagra concluded that there was "insufficient data" to decide which drug was best at treating erectile dysfunction. The researchers suggested doctors have patients try all three drugs to decide which works best for them personally.[2]

Levitra Studies

  • A meta-analysis of eight randomized, double-blinded, placebo-controlled clinical trials found Levitra greatly improved erectile function in men who also suffered from hypertension.[3]
  • In a randomized, double-blinded study of Japanese men suffering from erectile dysfunction, 90% of patients on Levitra saw significant improvements in achieving an erection. Furthermore, patients experienced no serious side effects. Mild side effects, such as flushing and headaches, were reported, however, and were more common on higher doses of the drug.[4]
  • A combination of Levitra, the antidepressant Zoloft (sertraline), and behavioral psychosexual therapy were found to moderately improve the symptoms of men suffering from premature ejaculation.[5]
  • Levitra improved erectile function in men with renal transplants, a demographic that frequently suffers from erectile dysfunction. Side effects experienced from taking Levitra were relatively mild and did not alter the results of renal function tests.[6]

Viagra Studies

  • In a study of 979 men who were taking Viagra, over 94% of participants reported improved erectile function over the course of 4 years of using the drug. Side effects and discontinuation of the drug due to "insufficient response" were rare. Long-term use of Viagra was shown to be effective and safe.[7]
  • An overview of clinical studies of Viagra found the drug to be safe and effective, even in some "difficult-to-treat" populations, such as patients with diabetes mellitus. Furthermore, the drug appears to have "beneficial effects" on the symptoms of several other chronic conditions, including some forms of premature ejaculation.[8]
  • While Viagra has not been found to treat sexual dysfunction in women, at least one study has found the drug is effective in treating symptoms associated with interstitial cystitis (bladder pain syndrome) in women.[9]

Side Effects

The common side effects of Viagra are usually mild and last a few hours, and may include facial flushing, an upset stomach, and headaches. Less common side effects are blurred vision, or perceiving a bluish tint in one's vision, and sensitivity to light. Levitra has shown additional common and usually mild side effects, including dizziness and nasal congestion.

Most side effects experienced from taking these drugs are temporary. Clinical studies have revealed that the frequency of these side effects decreases over time. However, a rare side effect, vision loss, has been reported with people who have used PDE5 inhibitors, including Viagra, Levitra, and Cialis. This loss of vision could be permanent and thus any vision-related side effects require an immediate visit to a doctor or medical facility. There is no evidence as yet that PDE5 inhibitors are the direct cause of vision loss.

The dependence or addiction liability of Viagra and Levitra is low. Many patients are able to have erections without these medications, though often not as easily or frequently.

Warnings

Those wanting to take Viagra or Levitra should get a prescription for the medication, based on a complete medical history. A person should reveal if he has an allergy to sildenafil or vardenafil, or any other medication, and report any incident of allergic reactions, such as a rash, hives, itching, shortness of breath, wheezing, coughing, or swelling of face, lips, tongue and throat.

Cardiovascular conditions should also be mentioned to doctors, as well as any renal or hepatic condition. Past and current drug use or addiction should be shared as well.

Drug Interactions

Other medications, such as Cimetidine (Tagamet), erythromycin, ketoconazole (Nizoral), itraconazole (Sporanox), and mibefradil (Posicor), can cause significant increases in the amount of sildenafil and vardenafil in the body, leading to a sudden drop in blood pressure. Patients on these medications should be observed carefully when taking Viagra or Levitra. Similarly, Rifampin decreases the blood levels of sildenafil and can reduce its effectiveness.

Vardenafil excretion is inhibited by erythromycin, ketoconazole (Nizoral), itraconazole (Sporanox), indinavir (Crixivan) and ritonavir (Norvir), so these drugs increase the concentration of vardenafil in the blood. To avoid potential complications, the dose of vardenafil should be reduced. Vardenafil reduces the concentration of ritonavir and indinavir in the blood, and can reduce the effect of these drugs.

Storage

Viagra and Levitra should be stored at room temperature and away from rooms with excessive moisture (e.g., bathroom, kitchen). Neither drug should be exposed to direct sunlight.

Chemistry

References

  • Wikipedia: Levitra
  • Wikipedia: Viagra

Source: http://www.diffen.com/difference/Levitra_vs_Viagra



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